Developmental & Stem Cell Biology
The research in Developmental and Stem Cell Biology seeks to understand the mechanisms controlling normal growth and development, and elucidate the mechanisms in diseased states. Scientists in these fields use modern and classic techniques developed in the areas of genetics, molecular biology, biochemistry, and cell biology, and ideas derived from the study of gene expression, cell motility, signal transduction and others to study a variety of biological questions.
The model organisms vary from yeast to mouse, but each allows facile manipulation of gene expression and function. While the specific questions are different, there is a common underlying experimental logic that is shared among the groups in this concentration. This allows for a lively exchange of ideas and the rapid transfer of experimental approaches from one group to another.
The training in this concentration is broad and consists of interdisciplinary education through research, specialized courses in advanced topics, and integration of several disciplines, and often involves collaborative efforts between preceptors from various fields. Recommended specialized courses may include animal physiology, vertebrate endocrinology, developmental biology, neuro-endocrinology, and human reproductive ecology.
Some of the research and training efforts of faculty in this concentration are coordinated through the Center for Reproductive Sciences whose dual mission is enhancing research in reproductive biology and its applications to human welfare, and optimizing the training of future research and teaching scientists in the broad area of reproductive biology. Depending on the specific research areas, outstanding students in this concentration may be nominated for support by the Cellular and Molecular Basis of Disease Training Program or the Training Program in Oncogenesis and Developmental Biology.
Cellular & Molecular Basis of Disease Training Program
Faculty List
Guillermo Ameer, PhD
Email: g-ameer@northwestern.edu
Research Interests: Bioartificial organ systems, cell delivery & transplantation, tissue engineering
Xiaomin Bao, PhD
Email: xiaomin.bao@northwestern.edu
Research Interests: Epigenomic regulation of stem cell maintenance and differentiation
Greg Beitel, PhD
Email: beitel@northwestern.edu
Research Interests: Molecular genetics of organ morphogenesis
Shelby Blythe, PhD
Email: shelby.blythe@northwestern.edu
Research Interests: Developmental control of chromatin structure & embryo pattern formation
Richard Carthew, PhD
Email: r-carthew@northwestern.edu
Research Interests: Quantitative and systems biology
Robert A. Holmgren, PhD
Email: r-holmgren@northwestern.edu
Research Interests: Cell-fate specification during development
Yevgenia Kozorovitskiy, PhD
Email: yevgenia.kozorovitskiy@northwestern.edu
Research Interests: Synaptic and circuit development in the basal ganglia
Carole LaBonne, PhD
Email: clabonne@northwestern.edu
Research Interests: Stem cells, gene regulatory networks and the evolution of vertebrates
Hojoon Lee, PhD
Email: hojoon.lee@northwestern.edu
Research Interests: Neurobiology of taste
Email: k-mayo@northwestern.edu
Research Interests: Gene regulation in the mammalian neuroendocrine system Richard I. Morimoto, PhD
Email: r-morimoto@northwestern.edu
Research Interests: Cell stress responses, molecular chaperones, and protein conformational disease Christian P. Petersen, PhD
Email: christian-p-petersen@northwestern.edu
Research Interests: Molecular and cellular basis of regeneration
Xiaozhong (Alec) Wang, PhD
Email: awang@northwestern.edu
Research Interests: Genetic analysis of protocadherin diversity in the central nervous system
Yue Yang, PhD
Email: yue.yang@northwestern.edu
Research Interests: Epigenetic programming of neural circuits